KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IREB2
All Species:
36.36
Human Site:
T391
Identified Species:
57.14
UniProt:
P48200
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P48200
NP_004127.1
963
105047
T391
F
F
P
V
D
N
V
T
L
K
H
L
E
H
T
Chimpanzee
Pan troglodytes
XP_523125
963
104993
T391
F
F
P
V
D
N
V
T
L
K
H
L
E
H
T
Rhesus Macaque
Macaca mulatta
XP_001107837
964
105069
T392
F
F
P
V
D
N
V
T
L
K
H
L
E
H
T
Dog
Lupus familis
XP_532364
964
105327
T392
F
F
P
V
D
N
V
T
L
K
H
L
E
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q811J3
963
104918
T392
F
F
P
V
D
N
V
T
L
R
H
L
E
H
T
Rat
Rattus norvegicus
Q62751
963
104783
T392
F
F
P
V
D
N
V
T
L
R
H
L
E
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513243
1011
110449
T439
F
F
P
V
D
N
V
T
V
K
H
L
E
H
T
Chicken
Gallus gallus
Q5ZLQ4
965
105344
T393
F
F
P
V
D
N
V
T
L
K
H
L
R
H
T
Frog
Xenopus laevis
Q6NTP2
955
104418
T385
F
F
P
V
D
S
V
T
L
Q
H
L
K
Q
T
Zebra Danio
Brachydanio rerio
XP_001341791
896
98752
S352
K
A
V
K
L
F
R
S
Y
D
D
Q
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524303
899
98560
L352
Y
L
K
A
T
Q
Q
L
R
N
Y
A
D
A
A
Honey Bee
Apis mellifera
XP_392993
890
98796
N352
L
R
N
Y
D
D
E
N
Q
N
P
N
F
S
E
Nematode Worm
Caenorhab. elegans
Q23500
887
96642
T353
T
D
D
S
Y
R
P
T
Y
T
T
T
L
K
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q42560
898
98134
C362
S
K
T
V
Y
S
S
C
L
E
L
N
L
E
D
Baker's Yeast
Sacchar. cerevisiae
P19414
778
85350
L247
P
K
D
I
I
L
K
L
A
G
I
T
T
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.1
92.5
N.A.
93.6
93.8
N.A.
84.4
82.1
68.5
62.9
N.A.
54.5
55.5
52.3
N.A.
Protein Similarity:
100
99.6
99.6
96.8
N.A.
96.6
97.1
N.A.
89.9
91.1
81
77
N.A.
72.4
71.8
67.5
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
93.3
93.3
73.3
0
N.A.
0
6.6
6.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
93.3
93.3
6.6
N.A.
20
13.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.1
26
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.5
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
0
0
0
0
7
0
0
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
7
14
0
67
7
0
0
0
7
7
0
7
0
7
% D
% Glu:
0
0
0
0
0
0
7
0
0
7
0
0
47
14
14
% E
% Phe:
60
60
0
0
0
7
0
0
0
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
60
0
0
54
0
% H
% Ile:
0
0
0
7
7
0
0
0
0
0
7
0
0
0
0
% I
% Lys:
7
14
7
7
0
0
7
0
0
40
0
0
7
7
7
% K
% Leu:
7
7
0
0
7
7
0
14
60
0
7
60
14
0
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
54
0
7
0
14
0
14
0
0
0
% N
% Pro:
7
0
60
0
0
0
7
0
0
0
7
0
0
0
0
% P
% Gln:
0
0
0
0
0
7
7
0
7
7
0
7
0
7
0
% Q
% Arg:
0
7
0
0
0
7
7
0
7
14
0
0
7
0
0
% R
% Ser:
7
0
0
7
0
14
7
7
0
0
0
0
7
7
0
% S
% Thr:
7
0
7
0
7
0
0
67
0
7
7
14
7
0
60
% T
% Val:
0
0
7
67
0
0
60
0
7
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
7
14
0
0
0
14
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _